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P18089?
Protein names
?Alpha-2B adrenergic receptor
Alpha-2 adrenergic receptor subtype C2
Alpha-2B adrenoreceptor
Alpha-2B adrenoceptor
Alpha-2BAR
蛋白中文名
?Alpha-2B肾上腺素能受体
Alpha-2 肾上腺素能受体亚型C2
Alpha-2B肾上腺素受体
?隐藏详细信息
Organism
?Homo sapiens
Gene ID
?151
Taxonomic identifier
?9606
Entry name
?ADA2B_HUMAN
Gene names
?ADRA2B
ADRA2L1, ADRA2RL1
Taxonomic lineage
?Eukaryota -> Metazoa -> Chordata -> Craniata -> Vertebrata -> Euteleostomi -> Mammalia -> Eutheria -> Euarchontoglires -> Primates -> Haplorrhini -> Catarrhini -> Hominidae -> Homo
Sequence length
?450
Sequence status
?Complete.
Protein existence
?Evidence at transcript level
Function
?Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.
Subcellular location
?Cell membrane; Multi-pass membrane protein.
Sequence similarities
?Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
Polymorphism
?A rare polymorphic framshift in position 451 produces a protein of 542 residues.
Cellular component
?Cell membrane; Membrane
Coding sequence diversity
?Polymorphism
[KW] Domain
?Transmembrane; Transmembrane helix
PTM
?Disulfide bond; Lipoprotein; Palmitate; Phosphoprotein
Molecular function
?Receptor; Transducer
Technical term
?3D-structure; Complete proteome
Gene Ontology Biological process
?cell-cell signaling
blood coagulation
positive regulation of neuron differentiation
Gene Ontology Cellular component
?integral to plasma membrane
Gene Ontology Molecular function
?protein binding

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Alpha-2B adrenergic receptor 的相关产品:
公司名称产品编号产品名称包装价格详细信息
Thermo Fisher? 查看代理商?PA1-27523?Anti-ADRA2B Polyclonal Antibody
?Anti-ADRA2B Polyclonalyabo狗亚体育
?50 μg?
Abnova? 查看代理商?H00000151-R02?ADRA2B Pre-design Chimera RNAi?10 nmol?$220.00
Abnova? 查看代理商?H00000151-R02?ADRA2B Pre-design Chimera RNAi?20 nmol?$264.00
Abnova? 查看代理商?PAB17354?ADRA2B polyclonal antibody
?ADRA2B polyclonalyabo狗亚体育
?100 ug?$298.00
Abgent? 查看代理商?AP8566c?ADRA2B Antibody (Center)
?ADRA2Byabo狗亚体育 (Center)
??
Abgent? 查看代理商?RI10152?ADRA2B predesign siRNA??
Abcam? 查看代理商?ab49689?alpha 2b Adrenergic Receptor antibody
?alpha 2b肾上腺素能受体yabo狗亚体育
??
Abcam? 查看代理商?ab91468?alpha 2b Adrenergic Receptor antibody
?alpha 2b肾上腺素能受体yabo狗亚体育
??
Novus? 查看代理商?H00000151-R02?Alpha 2b Adrenergic Receptor RNAi
?Alpha 2b肾上腺素能受体RNAi
??
assaybiotech? 查看代理商?C10415?Adrenergic Receptor alpha-2B Antibody
?肾上腺素能受体alpha-2Byabo狗亚体育
??

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