Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
A phosphate monoester + H(2)O = an alcohol + phosphate.
Binds 2 iron ions per subunit.
Coding sequence diversity
Disulfide bond; Glycoprotein
3D-structure; Complete proteome; Direct protein sequencing